Research & Development: Canadian Burden of Skin Disease from 1990 to 2017

microscope

Abstract Background: Skin diseases can have high morbidity that can be costly to society and individuals. To date, there has been no comprehensive assessment of the burden of skin disease in Canada. Objectives: To evaluate the burden of 18 skin and subcutaneous diseases from 1990 to 2017 in Canada using the Global Burden of Disease (GBD) data. […]

Research & Development: Artificial Intelligence May Help Predict Response to Immune Checkpoint Blockade in Patients With Metastatic Melanoma

microscope

Press Release from the American Association for Cancer Research   Link to page  PHILADELPHIA – A computational method that combines clinicodemographic variables with deep learning of pre-treatment histology images could predict response to immune checkpoint blockade among patients with advanced melanoma, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer […]

How To Take Control Of Your Body: Everything You Need To Know

man jogging on a lakefront trail photo for control of your body article

Practicing medicine is an inexact science. The body is a complex machine with nuanced capabilities and shortcomings. It is not a simple algorithm where X+Y=Z. Factors like lifestyle, diet, environmental considerations, and family history all add their own flavour on how a person will react to any illness. That means doctors are not only asked to practice “textbook science,” but […]

Research & Development: Temperature-dependent Cell Death Patterns

microscope

Temperature-dependent cell death patterns induced by functionalized gold nanoparticle photothermal therapy in melanoma cells Abstract Photothermal therapy (PTT) is a promising approach for cancer targeting therapy. However, the temperature-dependent killing of tumor cells in PTT remains unclear. In this study, we report necroptosis plays a role in the anti-tumor effects observed in gold nanorod (GNR)-mediated […]

The Truth About What Ontario Doctors are Paid

Ontario Doctor

The Ontario healthcare system is a truly wonderous execution of the bureaucracy. Large governing bodies, like the Ontario Medical Association and College of Nurses, are charged with interpreting dozens of provincial & federal legislative acts and countless regulations to provide Ontarians with the marvel that is the Ontario Healthcare Insurance Plan (OHIP). The total Ontario […]

Research & Development: Targeted-gene Silencing BRAF

microscope

Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem Abstract Melanoma is significantly associated with mutant BRAF gene, a suitable target for siRNA-based anti-melanoma therapy. However, a tumor-specific delivery system is a major hurdle for clinical applications. Here, we developed a novel nano-carrier, FA-GNR-siBRAF for safe […]

Why Skin Cancer Screening Is Needed Now More Than Ever

Doctor Hong and doctor Chan reviewing patient photos.

A recent report by the Toronto Star has exposed how the Coronavirus is affecting cancer care in Ontario. Their report states that there is a “sharp rise in the number of people coming to hospitals with advanced cancers” due to doctors prioritizing more serious cases, people avoiding medical centres, and the postponement of screening programs for breast, […]